Bilateral Breast Cancer: Analysis of Incidence, Characteristics and Outcome of the Disease.

2015 Mar;4(3):447-56. doi: 10.1002/cam4.378. Concordance index in the model of the worse characteristics was 0.816 (95% CI: 0.791-0.840), of the bilateral tumors was 0.819 (95% CI: 0.793-0.844), of the worse tumor was 0.807 (0.782-0.832), of the first tumor was 0.744 (0.728-0.763) and of the second tumor was 0.778 (0.762-0.794). Data were acquired from the prospectively maintained NUIG breast cancer database between 1988 and 2008. Occurrence and prognosis of contralateral carcinoma of the breast.
NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. 2006 Feb;141(2):155-60. doi: 10.1001/archsurg.141.2.155. Our results confirm international findings indicating worse outcomes from bilateral compared with unilateral breast cancer. 1990;2005(41):2331‐2337. If the cells have not spread much, a lumpectomy can be performed, in which case the surgeon removes only the tumor and surrounding tissue in an effort to get rid of the malignant cells. Another treatment available for bilateral breast cancer is chemotherapy, which is frequently given in the form of either a pill or an intravenous procedure in order to destroy malignant cells in both breasts. Synchronous and metachronous bilateral breast cancer: a long‐term experience. Synchronous and metachronous bilateral breast cancer: clinicopathologic characteristics and prognostic outcomes. 1990;2009(45):3000‐3007. All authors have declared no conflicts of interest. Medicine (Baltimore). Five (71.5%) underwent mastectomy and 2(28.5%) were treated by lumpectomy and axillary dissection. Epub 2016 Nov 28. The Role of FDG PET for Early Prediction of Response after Two Cycles of Epirubicin + Cyclophosphamide Neoadjuvant Chemotherapy in Breast Cancer. Copyright © 2010 Elsevier Ltd. All rights reserved. Necessary cookies enable core functionality. Eur J Cancer. Human epidermal growth factor receptor (HER2), was amplified in 23 of 69 tumors. https://doi.org/10.1016/j.breast.2010.10.004.

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Abstract P6-08-36: Uptake of preventive surgeries in a prospective cohort of BRCA1/2 healthy women, Abstract P6-13-02: Subcutaneous trastuzumab for the treatment of HER2+ breast cancer in Canada: A cost-minimization study, Abstract P6-12-07: A prospective pilot study of holistic wellness assessment using an innovative mobile technology in advanced breast cancer patients attending a tertiary cancer institute in India. BMC Cancer. While there was no significant difference in survival for patients with bilateral compared to unilateral tumour (p>0.05), the synchronous bilateral tumour was associated with poor overall survival (p=0.010) and disease free survival (p=0.013) in comparison to metachronous bilateral tumour.Conclusion: We observed significant differences in bilateral tumour characteristics compared to unilateral disease. Kota Arima, Presenter: Journal of Cancer Research ISSN: 0099-7013 Six patients presented with stage III and one with stage IV breast cancer. doi: 10.1097/MD.0000000000017725. Compared to unilateral cases, bilateral cancer patients were younger (0=0.021) and had smaller size (p=0.001) and earlier stage (p<0.001) tumours at diagnosis. The mean age was 51 years.

Data were acquired from the prospectively maintained NUIG breast cancer database between 1988 and 2008.

How do I Choose the Best Diet for Breast Cancer.

Objective: Via Ginevra 4, 6900 Lugano - CH© Copyright 2020 European Society for Medical Oncology All rights reserved worldwide. Uncertainty remains about the impact of bilateral breast cancer.  | 

2016 Dec 7;16(1):1230. doi: 10.1186/s12889-016-3863-6. Greater Anti-Angiogenic Effects with Docetaxel Compared with Anthracyclines in the Neoadjuvant Treatment of Breast Cancer. -, Ozturk A, Alco G, Sarsenov D, et al. Invasive ductal carcinoma was reported to be the most common type found in 10 (71.5%) breasts. doi: 10.1016/j.wneu.2019.04.262.

2019 Aug;128:e823-e834. The average tumor size was 46 mm. 48 BiBC and 1650 UBC were studied. Unfortunately, patients will likely need a mastectomy if the cancer has spread, which involves removing the entire breast, or even both breasts in advanced cases of bilateral breast cancer. Background: Despite the widespread adoption of breast conservation therapy in breast cancer, there is a dramatic increase in the rate of bilateral mastectomy in USA. HHS Get the latest public health information from CDC: https://www.coronavirus.gov. Please enable it to take advantage of the complete set of features! Twenty-five (24,7%) had metastatic disease at diagnosis. Nomograms that predict the survival of patients with adenocarcinoma in villous adenoma of the colorectum: a SEER-based study. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error.



Mammogram is a valuable tool in early detection.

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-, Lu W, Schaapveld M, Jansen L, et al. 2018;23:1591‐1600. Many patients also undergo chemotherapy, radiation treatment, or hormone therapy in conjunction with surgery to remove the cancer cells. Breast cancer screening programs: Review of merits, demerits, and recent recommendations practiced across the world. Factors associated with increased risk of bilateral breast cancer included lobular histology (p = 0.046), family history (p = 0.025) and metropolitan residence (p = 0.006). doi: 10.1097/MD.0000000000017903. Pathological and Patient Factors Affecting the Accuracy of Ultrasound Combined with Fine Needle Aspiration Cytology in Pre-Operative Staging of the Axilla in Breast Cancer.

The mean diameter of resected tumours measured by pathologists was 31,3 mm. We do not retain these email addresses.

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The calibration curves showed high concordance between the nomogram prediction and actual observation. ESMO is a Swiss-registered not-for-profit organisation.

In this study, we compared the clinicopathologic characteristics between the bilateral breast cancer (BiBC) and unilateral breast cancer (UBC) and investigated the role of CXC chemokine receptor type 4 (CXCR4) in BiBC. On pathology, ductal invasive carcinoma was found in 81,1% of cases whereas lobular invasive carcinoma in 10,9%. Most studies have defined SBBC as the presentation of bilateral breast cancer within 0–6 months of each other. Results: Hormone receptor status was positive in 78% of the cases. Positive lymph nodes accounted for 61% of all tumors. For more detailed information on the cookies we use, please check our Privacy Policy. Copyright © 2020 Elsevier B.V. or its licensors or contributors. Clipboard, Search History, and several other advanced features are temporarily unavailable.

Mammography showed opacity with malignant features in the contralateral breast in 55,4% of the cases. Symptoms of this issue include a lump in the tissue of the armpit or breast, sudden change in the shape or size of the breast … The website cannot function properly without these cookies, and can only be disabled by changing your browser preferences. J Microsc Ultrastruct. Please enable it to take advantage of the complete set of features! Nomogram predicting overall survival of rectal squamous cell carcinomas patients based on the SEER database: A population-based STROBE cohort study.

Detection and Diagnosis - Detection and Diagnosis-- Other, Cancer Epidemiology, Biomarkers & Prevention. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error, Nomogram for predicting the 3‐ and 5‐y survival probabilities of worse characteristics regardless of side in bilateral primary breast cancer.

Net reclassification index of the 3-year and the 5-year between them was 2.7% and -1.0%.

Although bilateral synchronous tumour was associated with poor outcome and overall survival, patients with metachronous disease do as well as patients with unilateral tumour. Whether synchronous or metachronous, both breasts often share the same histological type. Metachronous bilateral breast cancer presented poorer survival than synchronous bilateral breast cancer. Patient and second tumor characteristics were evaluated for an association with OS and RFS, as measured from diagnosis of the second tumor. Purpose There is controversy about whether patients with synchronous bilateral breast cancer (SBBC) have similar or worse outcomes compared with patients with unilateral breast cancer.

81772516/National Natural Science Foundation of China/International, Siegel RL, Miller KD, Jemal A. Get the latest public health information from CDC: https://www.coronavirus.gov. Characteristics and outcomes of unilateral and bilateral breast cancer were compared within an Australian multi-institutional cohort. Objective: Bilateral breast cancer is uncommon (1-2.6% of all patients with breast carcinoma).

The competing risk nomogram of the model of the worse characteristics may help clinicians predict survival simply and effectively. There has been conflicting evidence on the impact of bilateral breast cancer (BBC) on the survival and management of patients. Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. Clinicopathological characteristics of synchronous bilateral breast carcinomas. The prognosis of BPBC depended on bilateral tumors. Objective: American Journal of Cancer ISSN: 0099-7374, Abstracts: Thirty-Second Annual CTRC‐AACR San Antonio Breast Cancer Symposium‐‐ Dec 10‐13, 2009; San Antonio, TX, Sign In to Email Alerts with your Email Address.

Medical records of patients who were treated for breast cancer were reviewed at Khartoum Teaching Hospital, Sudan during a 5-year period of 1994 to 1999. Multivariate Cox hazard regression and competing risk analysis were to explore prognosis factors in training cohort. The five-year overall survival was 60%. Keywords:  |  Keisuke Kirita, Presenter: What are the patient expectations from palliative chemotherapy?  | 

Cancer Med. 2008 Dec;112(3):513-21. doi: 10.1007/s10549-007-9880-5.  |