document ETOP AACR 2020 French - final (2.22 MB). 2020 American Association for Cancer Research (AACR) Annual Meeting. ETOP AACR 2020 French - final We'll keep moving at the speed of oncology.
(2.20 MB), pdf Humanized Mice for Immuno-Oncology, Sounds of Science While the 2020 AACR annual meeting has moved online, cancer is still a very real threat.
Elizabeth Reap, Charles River, ePoster Presentation Available The combination of nivolumab and ipilimumab provided similar clinical benefit to that of chemotherapy when given as a frontline treatment for patients with advanced non–small cell lung cancer who had stable and treated brain metastases at baseline. Below please find the final AACR Annual Meeting 2020 slide deck in English, French, Chinese and Japanese, realised with support by Eli Lilly. Sheila Figel, PhD, a neuro-oncologic scientist with Roswell Park Comprehensive Cancer Center, discusses preclinical research with canonical and noncanonical that are displayed on the surface of cancer cells.
BioReperia In Collaboration with Charles River, Zebrafish patient tumor-derived xenograft models used for pre-clinical evaluation of CAN04 for lung and pancreatic cancer Julia Schueler, Charles River, ePoster Presentation Available Mon, 22 Jun 2020, 09:00 End. Rapid Readouts: JAVELIN Bladder 100 Phase III Interim Analysis, OncLive Events Scientific Interchange Workshop Series. Symposia. (2.22 MB), pdf June 24th 2020.
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You can download poster presentations below covering a variety of research topics, or click on the ePoster Presentations tab to watch the poster videos. (1.54 MB), document © 2020 MJH Life Sciences and OncLive. Workshops. (2.21 MB), pdf
A New Translational In Vivo Tool for Oncology Drug Discovery: Zebrafish Tumor Xenograft Model Grey Wolf Therapeutics in Collaboration with Charles River, ePoster Presentation Available Distributed Bio in Collaboration with Charles River, Co-administration of iRGD and therapeutic EGFR-antibodies Cetuximab and Panitumumab enhances drug penetration in NSCLC PDX based 3D multicellular spheroids IKP in Collaboration with Charles River, ePoster Presentation Available ETOP AACR 2020 Chinese - final pdf ETOP AACR 2020 French- final (1.54 MB).
Robert Nunan, Charles River, ePoster Presentation Available Julia Schuler, Charles River, ePoster Presentation Available
Planning the right experiment to address your specific research question can be challenging--that’s why CST scientists are here to help, virtually! ETOP AACR 2020 Japanese - final Schedule a virtual consultation …
Episode 20: A Tumor's Lair. Circulating tumor DNA clearance of EGFR mutation may be predictive of prolonged progression-free survival for patients with EGFR-mutant, MET-amplified non–small cell lung cancer with detectable ctDNA at baseline. An integrated in vitro and in vivo approach providing insights in immune modulation (2.20 MB), pdf Below please find the final AACR Annual Meeting 2020 slide deck in English, French, Chinese and Japanese, realised with support by Eli Lilly. Our scientists, in collaboration with our partners, proudly presented 19 scientific posters at AACR 2020. Robert Nunan, Charles River, Interplay between γδ T cells and breast cancer stem cells- a matter of life and death AACR ANNUAL MEETING 2020. A mouse orthotopic model of pancreatic cancer and response to treatment Proceedings: AACR Annual Meeting 2019 March 29–April 3, 2019; Atlanta, GA. …
The single mouse trial format predicts the sensitivity towards checkpoint inhibitor treatment in NSCLC PDX models in HuCD34NCG/CRL mice, an innovative triple immune deficient mouse strain pdf ETOP AACR 2020 English - final (1.47 MB). © 2020 Charles River Laboratories. document ETOP AACR 2020 English - final (2.21 MB). On April 6, due to the rapid escalation of the COVID-19 pandemic, … Sanne Holt, Charles River, Potent oral ERAP1 inhibitors modify the immunopeptidome in vivo and are novel immunotherapy agents document AACR Annual Meeting. Patients with breast cancer who harbor multiple PIK3A-mutant tumors achieved a higher clinical benefit from PI3Kα inhibition compared with single mutant tumors according to response analysis data from the SANDPIPER trial. Keep yours going strong with this collection of insights, tools, and resources prepared by our team. Robert Nunan, Charles River, ePoster Presentation Available Get ahead on your cancer research with this collection of eBooks, webinars, signaling pathways, and other materials.
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Info; Programme; Registration; NOTICE OF DECISION TO HOLD A VIRTUAL FORMAT ONLY. Presented by: Julia Schüler, DVM, PhD, Research Director, Charles River Leora Horn, MD, MSc, discusses data from an updated analysis of the phase 3 IMpower133 trial, which examined the first-line combination of atezolizumab (Tecentriq), carboplatin, and etoposide in small cell lung cancer.
Justin Moyers, MD, discusses real-world data and sociodemographic factors from an early analysis of the National Cancer Database associated with the treatment of adjuvant immunotherapy in stage III melanoma. The 2020 American Association for Cancer Research (AACR) Annual Meeting was scheduled to take place April 25-29, 2020 in San Diego, CA. The annual meeting of the AACR has been put on hold, but cancer continues. Enhanced anti-tumor lymphocyte function and frequencies measured by multichromatic flow cytometry in human CTLA-4 knock-in mice in a colorectal carcinoma model after treatment with ipilimumab
ETOP AACR 2020 English - final home; Dr. Moyers on Real-World Data With Adjuvant Immunotherapy in Melanoma. The second part will be held June 22-24, 2020, and features the NCI Director's Address, awards and lectures, a special session on NCI funding for research and training, and several presentations and poster sessions featuring NCI experts. https://iii.hm/13j7. pdf … The National Cancer Institute (NCI) is participating in this year's two-part American Association for Cancer Research (AACR) Virtual Annual Meeting. (2.13 MB), c/o IBCSG | Effingerstrasse 40 | 3008 Bern | Switzerland, ETOP Slide Deck from AACR Annual Meeting 2020, ETOP Publications and Meeting Contributions. All rights reserved. © 2020 MJH Life Sciences™ and OncLive.
Oral Presentations; Date Time Presenter Presentation Title; Monday, June 22: 2:08 PM - 2:28 PM : … In light of the COVID-19 pandemic, the meeting was moved to a virtual format as AACR Virtual Annual Meetings I and II, taking place April 27-28 and June 22-24, respectively. A full list of abstracts can be found on the AACR website. All rights reserved. Advanced Engineering Using CAR-T Display Libraries: Ultra-High Throughput Functional Screen June 22 – June 24, 2020 Virtual. A translational immuno-oncology platform to model T cell activation and Tex recovery in the tumor microenvironment Longitudinal characterization of patient-derived orthotopic xenograft brain tumor models Presented by: Robert Nunan, PhD, Group Leader, Charles River, Emergent Humanized Mouse Models Are Driving Immuno-Oncology Strategy ETOP AACR 2020 Japanese - final In the research community, we know our work doesn’t stop when crisis hits. Presented by: Tuulia Huhtala, PhD, Head of Biomarkers and Molecular Imaging, Charles River, How to Design & Execute Successful CAR-T Cell Therapy Programs (Available in The Source℠) (1.88 MB), document
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Use the tabs below to explore our range of posters, ePosters and resources from AACR 2020. Cancer Doesn't Stop For a Pandemic, Eureka Blog Hashtag: #AACR20. Evaluation of in vivo anti-tumor response of solid tumors in a novel immune cell-humanized NOD-Prkdcem26Cd52Il2rgem26Cd22/NjuCrl mouse model
The oral modified dysfunctional tyrosine SM-88 has demonstrated antitumor activity and appears to broadly effect the immune dynamics of the tumor microenvironment, according to early data from 2 xenograft studies.
Several DCEG scientists will present their research at the Virtual AACR Annual Meeting between June 22 - 24, 2020. Presented by: David Harris, PhD, Research Director, Oncology, Charles River, Bioinformatics: Mining Big Data to Discover Precision Oncology Therapies ETOP AACR 2020 Chinese - final Start. document ETOP AACR 2020 Chinese - final (2.20 MB). Abstracts: AACR Special Conference on Modernizing Population Sciences in the Digital Age February 19–22, 2019; San Diego, CA. AACR Virtual Annual Meeting II, June 22-24, 2020.
The HER2-selective TKI tucatinib (Tukysa) demonstrated potent antitumor activity alone and in combination with ado-trastuzumab emtansine (T-DM1; Kadcyla) in HER2-overexpressing breast cancer cell lines and xenograft models. Claudia Göttlich, PhD, Study Director, In Vitro, Charles River, When Immune Cells Invade a Tumor: Using the TME to Drive Your Oncology Research (1.47 MB), document Julia Schuler, Charles River, ePoster Presentation Available The neoadjuvant combination of nivolumab and ipilimumab continues to demonstrate a benefit in RFS compared with the combination given in the adjuvant setting in patients with stage III macroscopic melanoma. Thomas Metz, Charles River, Zebrafish patient tumor-derived xenograft models synergize with mouse-PDX models for understanding variation in anti-cancer drug responses Elizabeth Rainbolt, Charles River, A preclinical model using perfusion air culture of tumor tissue slices for personalized medicine In vitro cell based cytotoxicity and T cell activation assays to assess safety and efficacy of engineered T cell therapies